A Case Report of Cisplatin Induced Ototoxicity and Brief Review of Literature

  • Ahmad Najmi Associate Professor, Dept. of Pharmacology, AIIMS Bhopal
  • Ratinder Jhaj Additional Professor, Dept. of Pharmacology, AIIMS Bhopal
  • S. Balakrishnan Professor& Head, Dept. of Pharmacology, AIIMS Bhopal
  • Deepa Chaudhary Pharmacovigilance Associate, AIIMS Bhopal

Abstract

Ototoxicity refers to the hearing disorder those results from the temporary or permanent inner ear dysfunction after treatment with an ototoxic drug. Those of serious concern for permanent effects are the aminoglycoside antibiotics and the anticancer drug cisplatin. Cisplatin is a platinum coordination compound, which is used as first line drug in many cancers. Cisplatin ototoxicity can produce permanent hearing loss which can negatively affect the quality of life of a cancer patient. It is therefore important for health care professionals managing these patients to be aware of cisplatin ototoxic properties. This case of cisplatin induced ototoxicity points out the need of proper screening and audiological rehabilitation of patients with ototoxicity.

 

Published
2023-07-28
Issue
Volume 20 | Issue 1 | 2023
Section
CASE REPORT